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About 50% of patients will have a solid response to methylprednisolone.
Acute graft versus host disease generally occurs after allogeneic hematopoietic stem cell transplant (HSCT).Given the current ratio of related The clinical manifestations of acute GVHD represent the organs involved.The earliest and most common manifestation is skin GVHD.Symptoms most frequently start with donor engraftment, but may happen later.
Acute GVHD is a clinical diagnosis but, as many the symptoms of acute GVHD are non-specific, histologic confirmation, especially if the symptoms are atypical or involve just the liver or gut, may be extremely useful.].About 35%–50% of hematopoietic stem cell transplant (HSCT) recipients will develop acute GVHD.